Following Radical Pair Reactions in Solution: A Step Change in Sensitivity Using Cavity Ring-Down Detection

Miniaturized cavity ring-down detection in a liquid flow cell.

A novel method for applying cavity ring-down spectroscopy in the liquid phase, compatible with LC analyses, is presented. The core of the setup is a home-built cavity ring-down flow cell (cell volume 12 microL) that is constructed using a silicon rubber spacer, which is clamped leak-tight between two high-reflectivity mirrors. The mirrors are in direct contact with the liquid flow, which provid...

Trace moisture detection using continuous-wave cavity ring-down spectroscopy.

We have developed an instrument to measure trace concentrations of small hydride species in gases using continuous-wave cavity ring-down spectroscopy with near-infrared diode laser excitation. An rms baseline equivalent absorbance of 9.2 x 10(-11) cm(-1)/square root(n) is found, where n is the number of ring-down transients. When the 1396.376-nm absorption line of water is used, this correspond...

Optical heterodyne detection in cavity ring-down spectroscopy

Polarization-selective optical heterodyne detection is shown to enhance the practical sensitivity of cavity ring-down spectroscopy. Initial experiments demonstrate a signal-to-noise ratio above 31 dB. Minor improvements should yield shot-noise-limited operation. q 1998. Published by Elsevier Science B.V. All rights reserved.

Cavity Ring-down Biosensing

Cavity ring-down spectroscopy (CRDS) is an established technique for gases sensing that is newly emerging in the field of optical biosensing. This approach measures changes in the rate of decay of light injected into an optical resonator and relates them to optical loss along its length. This principle has recently been adapted for use in liquids, providing a highly sensitive method for quantit...

Cavity-locked ring-down spectroscopy